Monoethanolamine CAS#141-43-5
CAS Number: 141-43-5
Chemical Formula: C2H7NO
Synonyms:
Ethanolamine, ACS, 99+%
Ethanolamine, 99%, H2O 0.5% max
ETHANOLAMINE, REAGENTPLUS, >=99%
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: Colorless Liquid
Monoethanolamine CAS#141-43-5
Ethanolamine is a kind of viscous hygroscopic amino alcohol contains both amine and alcohol chemical groups. It is widely distributed inside the body and is a component of lecithin. It has many kinds of industrial applications. For example, it can be used in the production of agricultural chemicals including ammonia as well as the manufacturing of pharmaceuticals and detergents. It can also be used as a surfactant, fluorimetric reagent and removing agent of CO2 and H2S. In pharmaceutical field, ethanolamine is used as a Vascular Sclerosing agent. It also has antihistaminic property, which alleviates the negative symptoms caused by H1-receptor binding.
Monoethanolamine Chemical Properties |
Melting point | 10-11 °C(lit.) |
Boiling point | 170 °C(lit.) |
density | 1.012 g/mL at 25 °C(lit.) |
vapor density | 2.1 (vs air) |
vapor pressure | 0.2 mm Hg ( 20 °C) |
refractive index | n |
Fp | 200 °F |
storage temp. | Store at +15°C to +25°C. |
solubility | Soluble in benzene, ether, carbon tetrachloride. |
form | Liquid |
pka | 9.5(at 25℃) |
Specific Gravity | 1.012 |
color | APHA: ≤15 |
Odor | ammoniacal odor |
PH | 12.1 (100g/l, H2O, 20℃) |
Relative polarity | 0.651 |
biological source | synthetic |
explosive limit | 3.4-27%(V) |
Water Solubility | miscible |
Sensitive | Air Sensitive & Hygroscopic |
Merck | 14,3727 |
BRN | 505944 |
Henry's Law Constant | 1.61(x 10-10 atmm3/mol) at 20 °C (Bone et al., 1983) |
Exposure limits | TLV-TWA 3 ppm (~7.5 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 6 ppm (~15 mg/m3) (ACGIH); IDLH 1000 ppm (NIOSH). |
Dielectric constant | 31.940000000000001 |
Stability: | Stable. Flammable; incompatible with strong oxidizing agents, strong acids. Hygroscopic. |
Cosmetics Ingredients Functions | BUFFERING |
Cosmetic Ingredient Review (CIR) | Monoethanolamine (141-43-5) |
InChI | 1S/C2H7NO/c3-1-2-4/h4H,1-3H2 |
InChIKey | HZAXFHJVJLSVMW-UHFFFAOYSA-N |
SMILES | NCCO |
LogP | -2.3--1.91 at 25℃ |
Surface tension | 48.48mN/m at 293.15K |
CAS DataBase Reference | 141-43-5(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanolamine(141-43-5) |
EPA Substance Registry System | Ethanolamine (141-43-5) |
Safety Information |
Hazard Codes | T,C |
Risk Statements | 20/21/22-34-39/23/24/25-23/24/25-10-52/53 |
Safety Statements | 26-36/37/39-45-61 |
RIDADR | UN 2924 3/PG 3 |
OEB | B |
OEL | TWA: 3 ppm (8 mg/m3), STEL: 6 ppm (15 mg/m3) |
WGK Germany | 1 |
RTECS | KJ5775000 |
F | 8-10-23 |
Autoignition Temperature | 410 °C |
TSCA | TSCA listed |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29221100 |
Storage Class | 8A - Combustible corrosive hazardous materials |
Hazard Classifications | Acute Tox. 4 Dermal |
Hazardous Substances Data | 141-43-5(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 10.20 g/kg (Smyth) |
IDLA | 30 ppm |
Product Application Of Monoethanolamine CAS#141-43-5
Monoethanolamine is used primarily in pharmaceutical formulations for buffering purposes and in the preparation of emulsions. Other uses include as a solvent for fats and oils and as a stabilizing agent in an injectable dextrose solution of phenytoin sodium.
Monoethanolamine is also used to produce a variety of salts with therapeutic uses. For example, a salt of monoethanolamine with vitamin C is used for intramuscular injection, while the salicylate and undecenoate monoethanolamine salts are utilized respectively in the treatment of rheumatism and as an antifungal agent. However, the most common therapeutic use of monoethanolamine is in the production of ethanolamine oleate injection, which is used as a sclerosing agent.
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